La Ozonoterapia y el diagnóstico de RETINOSIS PIGMENTARIA

Se destaca la importancia de la ozonoterapia dentro de la terapéutica cubana para la retinosis pigmentaria. Se seleccionaron 2.656 pacientes portadores de retinosis pigmentaria, atendidos en el Centro Internacional de Retinosis Pigmentaria entre julio de 1992 y diciembre de 1999. A dichos pacientes se les aplicaron entre 10 y 15 sesiones de ozonoterapia combinada con electroestimulación y antioxidantes. Se observa que el 76% de los pacientes mantiene valores estables en su función visual. El 16% presenta diferentes grados de mejoría y el 8% sigue el curso natural de la enfermedad. La ozonoterapia es una terapéutica muy importante dentro del tratamiento cubano para la Retinosis Pigmentaria.

TEN YEAR STUDY IN PATIENTS SUFFERING FROM RETINITIS PIGMENTOSA AND TREATED WITH REPEATED CYCLES OF OZONE THERAPY.

Retinitis Pigmentosa is an hereditary disease of the retina which produces night blindness, peripheral visual field loss and narrowing of the central vision, which degenerates, after several years, in total blindness. This disease affects approximately 0.5 % of the world population and it is estimated that in Cuba suffer this disease, 3.1 per 10,000 habitants, with a great incidence in the central and west region of the country. In Cuba, it has been using ozone therapy like part of the treatment of Retinitis Pigmentosa, since November 1986, in "Salvador Allende" University Hospital. A study of the clinical evolution of 20 patients that have been treated (between 5 and 10 years) with repetitive cycles of ozone therapy was performed. No other therapy was associated. The ways of ozone application was autohemotherapy or rectal insufflation. A complete ophthalmologic examination was performed during this period. Snellen visual acuity, considering significant changes more than 2 lines and Goldmann kinetic visual field (V-4e target), considering significant changes increase in more than 10 grades and/or appearance of peripheric windows, were analyzed. The best results were achieved when ozone treatment is repeated, at least, twice a year, along all these years, with improvement of 70 % in the visual field and 42 % in the visual acuity. The rest of the patients maintained their visual field or visual acuity the same as the initial value, without worsen the disease. Any side effect was observed. The satisfactory results encourage to recommend its use in patients affected by Retinitis Pigmentosa.

EFECTS OF OZONE IN PATIENTS WITH RETINITIS PIGMENTOSA.

The effects of ozone in 50 patients with retinitis pigmentosa was evaluated in the Retinitis Pigmentosa Center, Camagüey, Cuba. The patients suffer of photophobia, photopsia and reduce vision on dark places. Considering that the patients with remission of two symptoms of the disease after the ozone treatment is considered as signs improvement, in this case all of them after the 7th and 8th ozone application didn't present photophobia and phototopsia, increasing also the quality of their vision (by means of improvement in the visual acuity and visual field). In spite of, after 6 month the appearance of signs and symptoms in all the patients took place. It is considered that the results are important and very useful as alternative in patients that not admit the surgery, repeating it twice a year